Publications and Abstracts

2011

  1. Castro OL, Gordeuk VR, Gladwin MT, Steinberg MH. Senicapoc trial results support the existence of different sub-phenotypes of sickle cell disease with possible drug-induced phenotypic shifts.
    Br J Haematol. 2011 Jul 7. doi: 10.1111/j.1365-2141.2011.08758.x. [Epub ahead of print] No abstract available.
    PMID: 21732927
  2. Duyne RV, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, Easley R, Klase Z, Nekhai S, Kehn-Hall K, Kashanchi F. Varying Modulation of HIV-1 LTR Activity by BAF Complexes.
    J Mol Biol. 2011 Jun 15. 
    PMID: 21699904
  3. Miasnikova G, Sergueeva AI, Nouraie M, Niu X, Okhotin DJ, Polyakova LA, Ganz T, Prchal JT, Gordeuk V. The heterozygote advantage of the Chuvash polycythemia VHLR200W mutation may be protection against anemia. Haematologica. 2011 May 23.
    PMID: 21606165
  4. Predictors of osteoclast activity in sickle cell disease patients.
    Nouraie M, Cheng K, Niu X, Moore-King E, Fadojutimi-Akinsi MF, Minniti CP, Sable C, Rana S, Dham N, Campbell A, Ensing G, Kato GJ, Gladwin MT, Castro OL, Gordeuk VR.
    Haematologica. 2011 May 5. 
    PMID: 21546502
  5. Machado RF, Barst RJ, Yovetich NA, Hassell KL, Kato GJ, Gordeuk VR, Gibbs JS, Little JA, Schraufnagel DE, Krishnamurti L, Girgis RE, Morris CR, Berman Rosenzweig E, Badesch DB, Lanzkron S, Onyekwere O, Castro OL, Sachdev V, Waclawiw MA, Woolson R, Goldsmith JC, Gladwin MT. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood. 2011 Apr 28.
    PMID: 21527519
  6. Ammosova T, Obukhov Y, Kotelkin A, Breuer D, Beullens M, Gordeuk VR, Bollen M, Nekhai S. Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175. PLoS One. 2011 Apr 21;6(4):e18985.
    PMID: 21533037
  7. McLaren CE, Garner CP, Constantine CC, McLachlan S, Vulpe CD, Snively BM, Gordeuk VR, Nickerson DA, Cook JD, Leiendecker-Foster C, Beckman KB, Eckfeldt JH, Barcellos LF, Murray JA, Adams PC, Acton RT, Killeen AA, McLaren GD. Genome-wide association study identifies genetic loci associated with iron deficiency. PLoS One. 2011 Mar 31;6(3):e17390.
    PMID: 21483845
  8. Gladwin MT, Kato GJ, Weiner D, Onyekwere OC, Dampier C, Hsu L, Hagar RW, Howard T, Nuss R, Okam MM, Tremonti CK, Berman B, Villella A, Krishnamurti L, Lanzkron S, Castro O, Gordeuk VR, Coles WA, Peters-Lawrence M, Nichols J, Hall MK, Hildesheim M, Blackwelder WC, Baldassarre J, Casella JF; DeNOVO Investigators. Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial. JAMA. 2011 Mar 2;305(9):893-902.
    PMID: 21364138 
  9. Thuma PE, van Dijk J, Bucala R, Debebe Z, Nekhai S, Kuddo T, Nouraie M, Weiss G, Gordeuk VR.Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia.
    J Infect Dis. 2011 Jan 15;203(2):211-9.
    PMID: 21288821
  10. Gordeuk VR, Minniti CP, Nouraie M, Campbell AD, Rana SR, Luchtman-Jones L, Sable C, Dham N, Ensing G, Prchal JT, Kato GJ, Gladwin MT, Castro OL. Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow up in children and adolescents with sickle cell anemia. Haematologica. 2011 Jan;96(1):33-40. Epub 2010 Sep 30.
    PMID: 20884713
  11. Debebe Z, Ammosova T, Breuer D, Lovejoy DB, Kalinowski DS, Karla PK, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk VR, Richardson DR, Nekhai S. Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9.
    Mol Pharmacol. 2011 Jan;79(1):185-96. 
    PMID: 20956357

2010

  1. Yoon D, Okhotin DV, Kim B, Okhotina Y, Okhotin DJ, Miasnikova GY, Sergueeva AI, Polyakova LA, Maslow A, Lee Y, Semenza GL, Prchal JT, Gordeuk VR. Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha. J Mol Med 2010;88:523-530.
  2. Aliyu ZY, Suleiman A, Attah E, Mamman AI, Babadoko A, Nouraie M, Mendelsohn L, Kato GJ, Gordeuk VR, Gladwin MT. NT-proBNP as a marker of cardiopulmonary status in sickle cell anaemia in Africa. Br J Haematol. 2010;150:102-107.
  3. Nouraie M, Reading NS, Campbell A, Minniti CP, Rana SR, Luchtman-Jones L, Kato GJ, Gladwin MT, Castro OL, Prchal JT, Gordeuk VR. Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia. Br J Haematol. 2010;150:218-225.
  4. Xu M, Kashanchi F, Foster A, Rotimi J, Turner W, Gordeuk VR, Nekhai S. Hepcidin induces HIV-1 transcription inhibited by ferroportin. Retrovirology. 2010 Dec 2;7(1):104. [Epub ahead of print] PubMed PMID: 21126372.
  5. Debebe Z, Ammosova T, Breuer D, Lovejoy D, Kalinowski D, Karla P, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk V, Richardson DR, Nekhai S. Iron Chelators of the DpT and BpT Series Inhibit HIV-1 Transcription: Identification of Novel Cellular Targets - Iron, CDK2 and CDK9. Mol Pharmacol. 2010 Oct 25.[Epub ahead of print] PubMed PMID: 20956357.
  6. Gordeuk V, Minniti CP, Nouraie M, Campbell AD, Rana S, Luchtman-Jones L, Sable C, Dham N, Ensing G, Prchal JT, Kato GJ, Gladwin MT, Castro OL. Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow-up in children and adolescents with sickle cell anemia. Haematologica 2010 Sep 30. [Epub ahead of print] PubMed PMID: 20884713.
  7. Kasvosve I, Debebe Z, Nekhai S, Gordeuk VR. Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-alpha and macrophage migration inhibitory factor concentrations in African children. Clin Chim Acta. 2010 Sep 6;411(17-18):1248-52. Epub 2010 May 10. PubMed PMID: 20460119; PubMed Central PMCID: PMC2921676.
  8. Merat S, Rezvan H, Nouraie M, Jafari E, Abolghasemi H, Radmard AR, Zaer-rezaii H, Amini-Kafiabad S, Maghsudlu M, Pourshams A, Malekzadeh R, Esmaili S. Seroprevalence of hepatitis C virus: the first population-based study from Iran. Int J Infect Dis. 2010 Sep;14 Suppl 3:e113-6. Epub 2010 Apr 2. PubMed PMID: 20362479.
  9. Gladwin MT, Barst RJ, Castro OL, Gordeuk VR, Hillery CA, Kato GJ, Kim-Shapiro DB, Machado R, Morris CR, Steinberg MH, Vichinsky EP. Pulmonary hypertension and NO in sickle cell. Blood. 2010 Aug 5;116(5):852-4. PubMed PMID: 20688967; PubMed Central PMCID: PMC2918336.
  10. Sohrabi S, Nouraie M, Khademi H, Baghizadeh S, Nasseri-Moghaddam S, Malekzadeh R. Epidemiology of uninvestigated gastrointestinal symptoms in adolescents: a population-based study applying the Rome II questionnaire. J Pediatr Gastroenterol Nutr. 2010 Jul;51(1):41-5. PubMed PMID: 20543723.
  11. Khademi H, Etemadi A, Kamangar F, Nouraie M, Shakeri R, Abaie B, Pourshams A, Bagheri M, Hooshyar A, Islami F, Abnet CC, Pharoah P, Brennan P, Boffetta P, Dawsey SM, Malekzadeh R. Verbal autopsy: reliability and validity estimates for causes of death in the Golestan Cohort Study in Iran. PLoS One. 2010 Jun 17;5(6):e11183. PubMed PMID: 20567597; PubMed Central PMCID: PMC2887437.
  12. Ufearo H, Kambal K, Onojobi GO, Nouraie M, Agbemabiese C, Diaz S, Aggarwal A, Aliyu Z, Taylor RE, Gordeuk VR. Complete blood count, measures of iron status and inflammatory markers in inner-city African Americans with undiagnosed hepatitis C seropositivity. Clin Chim Acta. 2010 May 2;411(9-10):653-6. Epub 2010 Feb 1. PubMed PMID: 20117104; PubMed Central PMCID: PMC2847047.
  13. Nouraie M, Hosseinkhah F, Brim H, Zamanifekri B, Smoot DT, Ashktorab H. Clinicopathological features of colon polyps from African-Americans. Dig Dis Sci. 2010 May;55(5):1442-9. Epub 2010 Mar 12. PubMed PMID: 20225129.
  14. McLaren CE, Barton JC, Eckfeldt JH, McLaren GD, Acton RT, Adams PC, Henkin LF, Gordeuk VR, Vulpe CD, Harris EL, Harrison BW, Reiss JA, Snively BM. Heritability of serum iron measures in the hemochromatosis and iron overload screening (HEIRS) family study. Am J Hematol. 2010 Feb;85(2):101-5. PubMed PMID: 20095037.
  15. Pourshams A, Khademi H, Malekshah AF, Islami F, Nouraei M, Sadjadi AR, Jafari E, Rakhshani N, Salahi R, Semnani S, Kamangar F, Abnet CC, Ponder B, Day N, Dawsey SM, Boffetta P, Malekzadeh R. Cohort Profile: The Golestan Cohort Study—a prospective study of oesophageal cancer in northern Iran. Int J Epidemiol. 2010 Feb;39(1):52-9. Epub 2009 Mar 30. PubMed PMID: 19332502.
  16. Merat S, Khadem-Sameni F, Nouraie M, Derakhshan MH, Tavangar SM, Mossaffa S, Malekzadeh R, Sotoudeh M. A modification of the Brunt system for scoring liver histology of patients with non-alcoholic fatty liver disease. Arch Iran Med. 2010 Jan;13(1):38-44. PubMed PMID: 20039768.
  17. Complete blood count, measures of iron status and inflammatory markers in inner-city African Americans with undiagnosed hepatitis C seropositivity. Ufearo H, Kambal K, Onojobi GO, Nouraie M, Agbemabiese C, Diaz S, Aggarwal A, Aliyu Z, Taylor RE, Gordeuk VR. Clin Chim Acta. 2010 May 2;411(9-10):653-6. Epub 2010 Feb 1. PMID: 20117104
  18. Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha. Yoon D, Okhotin DV, Kim B, Okhotina Y, Okhotin DJ, Miasnikova GY, Sergueeva AI, Polyakova LA, Maslow A, Lee Y, Semenza GL, Prchal JT, Gordeuk VR. J Mol Med. 2010 May;88(5):523-30. Epub 2010 Feb 8. PMID: 20140661
  19. Heritability of serum iron measures in the hemochromatosis and iron overload screening (HEIRS) family study. McLaren CE, Barton JC, Eckfeldt JH, McLaren GD, Acton RT, Adams PC, Henkin LF, Gordeuk VR, Vulpe CD, Harris EL, Harrison BW, Reiss JA, Snively BM. Am J Hematol. 2010 Feb;85(2):101-5. PMID: 20095037
  20. Clinicopathological features of colon polyps from African-Americans. Nouraie M, Hosseinkhah F, Brim H, Zamanifekri B, Smoot DT, Ashktorab H. Dig Dis Sci. 2010 May;55(5):1442-9. Epub 2010 Mar 12.PMID: 20225129