Publications

Manuscripts

  1. Ashenafi, M., Ammosova, T., Nekhai, S., and Byrnes, W.M. 2014. Purification and characterization of aminoglycoside phosphotransferase APH(6)-Id, a streptomycin-inactivating enzyme. Mol. Cell. Biochem. 387:207-216. PMID: 24248535. NIHMSID #564173
  2. Zhang, X., Zhang, W., Ma, S.F., Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai, S., Nouraie, M., Wade, M.S., Prchal, J. T., Garcia, J.G., Machado, R. F., and Gordeuk, V.R. 2014. Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing. Blood Cells Mol Dis. 52:35-45. PMC3852195
  3. Salomon-Andonie J, Miasnikova G, Sergueeva A, Polyakova LA, Niu, X., Nekhai S., and Gordeuk, V.R. 2013. Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood. Blood, 122:3088-9. PMC3811180
  4. Tomasic NL, Piterkova L, Huff C, Bilic E, Yoon D, Miasnikova GY, Sergueeva AI, Niu X, Nekhai S, Gordeuk V, Prchal JT. 2013.The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W). Haematologica 98: 560-567. PMC3659987
  5. Zhou ZH, Kumari N, Nekhai S, Clouse KA, Wahl LM, Yamada KM, Dhawan S. 2013. Heme oxygenase-1 induction alters chemokine regulation and ameliorates human immunodeficiency virus-type-1 infection in lipopolysaccharide-stimulated macrophages. Biochem. Biophys. Res. Commun. 435: 373-377. PMID: 23665328. NIHMSID #564195
  6. Nekhai, S., Petukhov, M., and Breuer, D. 2014. Regulation of CDK9 activity by phosphorylation and dephosphorylation. BioMed Research International. 2014:, Article ID 964964. PMCID in submission.
  7. Zhou, Z.-H., Kumari, N., Catalano, J., Nekhai, S., Wise, J., Yamada, K. M., and Dhawan, S. 2014. Heme oxygenase-1-mediated host cell response inhibits the susceptibility of prostate cancer cells to retroviral infection and retards their proliferation, Current Trends in Immunology. In press. NIHMSID #564211
  8. Darbari DS, Nouraie M, Taylor JG, Brugnara C, Castro O, Ballas SK. 2014. Alpha-thalassaemia and response to hydroxyurea in sickle cell anaemia. Eur. J. Haematol. 92(4):341-5. PMC3962692

Presentations

  1. Ivanov, A., & Nekhai, S. A. (2013). Ferroportin Q248H Mutation Prevents Its Ubiquitination. Blood, 122(21), 2196-2196.
  2. Kumari, N., Xu, M., Kovalskyy, D., Dhawan, S., & Nekhai, S. (2012, November). Novel 2-Phenyl-1-Pyridin-2yl-Ethanone (PpY) Based Iron Chelators Increase Expression of IkB alpha and Heme Oxygenase-1 and Inhibit HIV-1. In BLOOD (Vol. 120, No. 21).
  3. Zhang, W., Ma, S. F., Desai, A. A., Miasnikova, G. Y., Sergueeva, A., Ammosova, T., & Gordeuk, V. R. (2013). Genetic Association Of a MAPK8 Expression Quantitative Trait Locus With Pre-Capillary Pulmonary Hypertension In Sickle Cell Disease. Blood, 122(21), 991-991.
  4. Kumari, N., Breuer, D., Mclean, C., Ammosova, T., & Dhawan, S. (2013). Induction of Ferroportin, Erg-1, p21 and IKBα In Sickle Cell Disease May Contribute To HIV-1 Inhibition. Blood, 122(21), 2250-2250.
  5. Nekhai, S., Kumari, N., Foster, A., Diaz, S., Kovalskyy, D., Gordeuk, V. R., & Dhawan, S. (2013, May). HIV-1 INFECTION AND IRON: ROLE OF HEME-OXYGENASE-1 AND FERROPORTIN. In AMERICAN JOURNAL OF HEMATOLOGY (Vol. 88, No. 5, pp. E123-E123).
  6. Nekhai, S. A. (2013). Heme and Iron Chelators Inhibit HIV-1 Through The Induction Of Heme Oxygenase 1, Ferroportin and IKBα. Blood, 122(21), 2198-2198.
  7. Kumari, N., Kovalsky, D., Breuer, D., Niu, X., & Nekhai, S. (2013). Iron depletion by iron chelators or ferroportin inhibits HIV-1 through the induction of HIF1α, p21 and IKBα and the inhibition of CDK9 and CDK2. Retrovirology, 10(Suppl 1), P63.
  8. Chasnyk, V., Nekhai, S., Hynes, A., Ammosova, T., Obukhov, Y., Gaidar, E., ... & Nikitina, T. (2013, October). Proteomic Profile Of Tears: Can It Help To Diagnose Juvenile Arthritis-Associated Uveitis Prior To The Clinical Signs Of Joints Inflammation. In ARTHRITIS AND RHEUMATISM (Vol. 65, pp. S806-S806).
  9. Kumari N, Kovalsky D., Breuer D., Niu X., and Nekhai, S. (2013). Iron depletion by iron chelators or ferroportin inhibits HIV-1 through the induction of HIF1α, p21 and IKBα and the inhibition of CDK9 and CDK2. Frontiers in Retrovirology, September 2013, Cambridge, UK
  10. Kumari, N, Xu,M., Foster, A., Diaz, S., Kovlaskyy,D, Gordeuk, V.R, Dhawan,S., and Nekhai, S. (2013) HIV-1 infection and iron: role of heme-oxygenase-1 and ferroportin. International BioIron Society meeting, April 2013, London, UK
  11. Reid, T-E.; Basant, N.; Kumari, N.; Nekhai, S.; Habib, M.; Wang, X. S. Novel structure-based approaches toward highly selective HDAC2 inhibitors to treat Alzheimer's disease. 1st Annual Howard University Research Day. Washington, DC (Award for Graduate Student, Apr. 2013)
  12. Reid, T-E.; Basant, N.; Kumari, N.; Nekhai, S.; Habib, M.; Wang, X. S. Novel structure-based approaches toward highly selective HDAC2 inhibitors with dual roles as imaging probes and therapeutics to treat Alzheimer's disease. 10th Annual World Congress of Society for Brain Mapping and Therapeutics. Baltimore, MD (May 2013)
  13. Reid, T-E.; Basant, N.; Nekhai, S.; Wang, X. S. Novel structure-based approaches toward highly selective HDAC2 inhibitors to treat Alzheimer's disease. Regional American Association of Pharmaceutical Scientists (AAPS) Meeting & Research Forum. Morgantown, WV (May 2013)
  14. Reid, T-E.; Basant, N.; Nekhai, S.; Wang, X. S. Novel structure-based approaches toward highly selective HDAC2 and HDAC3 inhibitors to treat Alzheimer's disease. 7th Annual Drug Discovery for Neurodegeneration Conference. San Francisco, California (Alzheimer’s Drug Discovery Foundation Outstanding Young Investigator Award, Feb. 2013)
  15. Castro, OL.; O’Neal, P.; Nouraie M.; Hydroxyurea Treatment in Sickle Cell Disease: Theoretic Leukemia Risk Versus Survival Benefit. Miami, Florida (Foundation for sickle cell research meeting, April. 2014)
  16. Nouraie, M.; Gordeuk, VR.; Sepsis and stroke but not acute chest syndrome are contemporary independent predictors of inpatient mortality in sickle cell disease patients Miami, Florida (Foundation for sickle cell research meeting, April. 2014)
  17. Nouraie, M.; Gordeuk, VR.; Factors affecting length of stay, hospitalization cost and in-patient mortality in sickle cell patients admitted with acute vaso-occlusive crisis. Miami, Florida (Foundation for sickle cell research meeting, April. 2014)
  18. Gopie, P.; Sri Lakshmi, Y.; O’Neal P.; Nouraie, M.; High hospital 30-day readmission rate in young sickle cell disease (SCD) adults with sickle cell crisis despite hydroxyurea therapy. Miami, Florida (Foundation for sickle cell research meeting, April. 2014)
  19. Sri Lakshmi, Y.; Gopie, P.; O’Neal, P.; Nouraie, M.; Prevalence of Renal Dysfunction and Its Effect on Length of Hospitalization and Mortality in Sickle Cell Disease. Miami, Florida (Foundation for sickle cell research meeting, April. 2014)