Research at the Center for Sickle Cell Disease

What Kind of Research is Done at the Center?

The Center has a long history of major participation and leadership in national and international research projects that have led to the development of effective therapies for sickle cell disease. With many of the basic molecular issues in sickle cell disease being better understood, major research efforts now focus primarily on clinical issues such as treatment for the disease. 

Much of the Center’s research is also devoted to the prevention and treatment of excess body iron, high blood pressure in the lungs, and to the study of a natural chemical called nitric oxide.  Low nitric oxide levels impair the flow of blood so nitric oxide administration is being investigated for possible therapeutic applications in sickle cell disease.  The role that vitamin deficiencies play in the manifestations of sickle cell disease is also being investigated.